The authors report a rare case of herniation and incarceration of the gallbladder at the site of abdominal drainage tube deployment in a patient undergoing treatment for aortic valve disease. An incarcerated postoperative ventral hernia was confirmed by contrast-enhanced CT of the abdomen. Emergency surgery was not indicated due to spontaneous reduction, short duration of incarceration and no peritoneal signs. This case reminds us the possibility of ventral hernias, containing the gallbladder, at the site of abdominal drainage tube deployment. According to the literature, untimely diagnosis of this event can result fatal consequences.
Gallbladder , Hernia, Ventral , Diagnosis, Differential , Drainage , Gallbladder/diagnostic imaging , Gallbladder/surgery , Hernia, Ventral/diagnosis , Humans
The aim of this study was to analyze quality-of-life parameters in patients with coronary heart disease in Chelyabinsk region. The number of patients with coronary heart disease who took part in this research was 830 people. The data were collected with using of application form that was supplemented by the Russian-language questionnaire SF-36. We determined the medical and social characteristics, the assessment of the conditions and lifestyle of patients with coronary heart disease, and the subjective assessment of the quality of life by themselves. We have been revealed statistically significant differences in assessing the quality of life by patients of different territorial groups. The data should be differentially use in developing of regional and territorial programs in order to reduce mortality from coronary heart disease.
Coronary Disease , Myocardial Ischemia , Humans , Life Style , Quality of Life , Surveys and Questionnaires
AIM: To evaluate the efficacy and safety of cortexin in the complex of rehabilitation measures for verticalization in patients with ischemic stroke in the acute period. MATERIAL AND METHODS: The study included 90 patients with hemispheric ischemic stroke. Patients of the first group (n=30) received cortexin in a dose of 20 mg per day intramuscularly for 10 days, along with basic therapy during early verticalization. Patients of the second group (n=30) received basic therapy during early verticalization and patients of the third group (n=30) received only basic therapy without verticalization. To assess the severity of condition, NIHSS, modified Rankin scale, the Barthel index, the Rivermead mobility index, MMSE, MOCA were used. To study cardiovascular function in patients, the segmental part of the autonomic nervous system was studied: a test with isometric load, a Valsalva test, a test based on the change in heart rate with slow deep breathing. All studies were conducted before and 10-14 days after treatment. RESULTS AND CONCLUSION: The most complete regression of neurological deficits and manifestations of cardiac autonomic neuropathy during the acute period of ischemic stroke was observed in the group of patients treated with cortexin (20 mg per day for 10 days), along with basic therapy and early verticalization, compared to the groups, which received basic therapy with early verticalization or basic therapy without verticalization.
Brain Ischemia , Intercellular Signaling Peptides and Proteins , Stroke , Brain Ischemia/drug therapy , Humans , Intercellular Signaling Peptides and Proteins/therapeutic use , Peptides , Stroke/drug therapy , Treatment Outcome
AIM: To make a critical assessment of the therapeutic effect of complex therapy with cortexin and recognan (citicoline) for cognitive impairments in patients with chronic cerebrovascular pathology. MATERIAL AND METHODS: Presented is an analysis of results of the multicenter observation program to assess the efficacy of cortexin and recognan (citicoline) in the treatment of cognitive impairments in patients with chronic cerebrovascular pathology. Three hundred and nine patients with chronic cerebrovascular pathology, including 134 (43.4%) men and 175 (56.6%) women, aged from 30 to 80, average age 63.4±9.4 years, with confirmed cognitive deficit were examined. The diagnosis was established on the basis of complaints, case reports, the results of CT/MRI studies, as well as assessments of the neurological status and cognitive functions. Cognitive impairments were confirmed by the number of points on the Mini-mental state examination (MMSE) and the Clock drawing test. The assessment of depression was made with the Mini Geriatric Depression Scale (MGDS). All patients received cortexin and recognan (citicoline) ('Geropharm', Russia) at doses 10 mg/day for 10 days and 1000 mg/day for 1 month, respectively. RESULTS AND CONCLUSION: Complex therapy with cortexin and recognan (citicoline) showed high efficacy in the treatment of vascular cognitive disorders. The results of the study allow us to recommend the complex administration of cortexin and recognan (citicoline) ('Geropharm', Russia) in doses of 10 mg/day for 10 days and 1000 mg/day for 1 month, respectively, for chronic cerebrovascular pathology.
Cognitive Dysfunction , Adult , Aged , Aged, 80 and over , Cytidine Diphosphate Choline , Female , Humans , Intercellular Signaling Peptides and Proteins , Male , Middle Aged , Peptides , Russia
Cardiac Surgical Procedures/adverse effects , Colonic Pseudo-Obstruction/diagnosis , Intestine, Large/diagnostic imaging , Postoperative Complications/etiology , Colonic Pseudo-Obstruction/therapy , Erythromycin/therapeutic use , Female , Gastrointestinal Agents/therapeutic use , Heart Failure/etiology , Humans , Intubation, Gastrointestinal , Middle Aged , Multidetector Computed Tomography , Neostigmine/therapeutic use , Tomography, Spiral Computed , Treatment Outcome
AIM: To study the efficacy and prolonged effect of repeated treatment with low-doses of the neuroprotection drug cortexin (30 mg, (10+10+10, morning, noon, day), daily) in patients in the acute period of hemispheric ischemic stroke. MATERIAL AND METHODS: One hundred and twenty-two patients with hemispheric ischemic stroke were studied. Patients of the first group (n=30) received cortexin in a dose of 20 mg (10+10) intramuscularly along with basic therapy, patients of the second group (n=30) received two courses of cortexin in the same dose for 10 days each with a break of 10 days in-between, patients of the third group (n=30) received only basic therapy, patients of the fourth group (n=32) received cortexin in a dose of 30 mg (10+10+10), two courses for 10 days each with a break of 10 days in-between. NIHSS, modified Rankin scale, Barthel index, Rivermead mobility index, MMSE, MOCA-test were used to evaluate the severity of the condition. RESULTS AND CONCLUSION: The most complete regression of neurological deficit during the acute period of ischemic stroke was observed in the fourth group of patients (30 mg (10+10+10) of cortexin, two courses) compared to the 1-3 groups.
Brain Ischemia , Stroke , Humans , Injections, Intramuscular , Neuroprotective Agents , Severity of Illness Index , Treatment Outcome
It was found that seven strains of bacteria can cause corrosion damage to aluminum, its alloys, and zinc. With respect to the studied metals, the most active bacteria were Proteus vulgaris 1212 and Pseudomonas aeruginosa 969. Superoxide anion radicals were demonstrated to play a role in the initiation of corrosive damage to aluminum and zinc, while bacterial exometabolites participate in the later stages of this process.
Biofilms/growth & development , Metals , Proteus vulgaris/physiology , Pseudomonas aeruginosa/physiology , Superoxides/metabolism , Corrosion
Biological corrosion of ADO quality aluminum and aluminum-based construction materials (alloys V65, D16, and D16T) was studied. Thirteen microscopic fungus species and six bacterial species proved to be able to attack aluminum and its alloys. It was found that biocorrosion of metals by microscopic fungi and bacteria was mediated by certain exometabolites. Experiments on biocorrosion of the materials by the microscopic fungus Alternaria alternata, the most active biodegrader, demonstrated that the micromycete attack started with the appearance of exudate with pH 8-9 on end faces of the samples.
Alloys/chemistry , Aluminum/chemistry , Bacteria/metabolism , Biofilms , Fungi/metabolism , Construction Materials , Corrosion , Hydrogen-Ion Concentration , Surface Properties
The elastic properties of an inhomogeneous medium with chaotic structure were derived within the framework of a fractal model using the iterative averaging approach. The predicted values of a critical index for the bulk elastic modulus and of the Poisson ratio in the vicinity of a percolation threshold were in fair agreement with the available experimental data for inhomogeneous composites.
